Studies on mikamycin B lactonase. III. Purification and some properties of mikamycin B lactonase.
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چکیده
منابع مشابه
Studies on mikamycin B lactonase. I. Degradation of mikamycin B by Streptomyces mitakaensis.
Some intensive studies on the inactivation mechanisms of clinically important antibiotics such as penicillin1), chloramphenicol2) and aminoglycosidic antibiotics3,4) have been reported. Derivations and cleavages of these antibiotic molecules were the mechanisms of inactivation in resistant organisms. Another aspect of antibiotic inactivation so far studied is the action of soil microbes. ARGOUD...
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A 3-hydroxypicolinic acid activating enzyme from etamycin producing Streptomyces griseoviridus has been purified to apparent homogeneity. Etamycin is a member of mikamycin B antibiotics, chromopeptide lactones, which contain 3-hydroxypicolinic acid (3-HPA) as the chromophoric group. The enzyme catalyzes both the 3-HPA-dependent ATP-pyrophosphate exchange and the formation of 3-HPA adenylate fro...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1976
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.40.1559